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Frontier Pharmaceutical, Inc.

Studies

DioxiBrite™ Toothpaste

  • Efficacy Evaluation of a Chlorine Dioxide Containing Toothpaste (DioxiBrite™) on Plaque and Gingivitis
L. Mueller-Joseph, State University of New York at Farmingdale, Dept. of Dental Hygiene, Farmingdale, NY

A double blind study in 14 patients showed that DioxiBrite™ toothpaste was statistically significantly (p> 0.0482) better than Colgate's TOTAL® for plaque reduction, and as effective in treating gingivitis. These results are significant given that TOTAL has FDA approval for these indications.

  • Efficacy Evaluation of a Chlorine Dioxide Toothpaste (DioxiBrite™) on Plaque and Gingivitis

A double blind study in 55 patients confirmed the results of the previous study by demonstrating that DioxiBrite™ toothpaste was better than Colgate's TOTAL on plaque.

DioxiRinse™ Mouthwash

  • Effect of DioxiRinse™ Mouthwash on Oral Malodor: Clinical and Microbiological Pilot Study
S. Nachnani, University Health Resources Group, Inc., Culver City, CA

A one-week study in 15 patients with halitosis demonstrated that DioxiRinse mouthwash effectively reduced oral malodor, volatile sulfur compounds, and microbial counts. Study subjects commented that they "liked the mouthwash".

BioClenz™(formerly named DioxiClear) Dental Line Cleaner

  • Evaluation of DioxiClear™ as a treatment for dental unit waterline biofilms and as a water contamination control agent
R. Puttaiah, Baylor College of Dentistry TAMUS HSC, Dallas, TX
  • Utilization of two concentrations of ClO2 Cleaner in controlling dental waterline contamination
Presented at the 30th Annual Meeting of the American Association for Dental Research, March 2001. Chicago, Ill. J Dent Research Vol. 80 Special Issue [AADR Abstracts]. Abstract # 1066.>
R. Puttaiah, et al, Baylor College of Dentistry TAMUS HSC, Dallas, TX

In two studies, BioClenz was tested for its efficacy as a dental line decontaminant and biofilm remover.

DioxiDent™ Liquid

  • Clinical and Microbiological Efficacy of Chlorine Dioxide (ClO2) in the Management of Chronic Atrophic Candidiasis
Submitted for Publication in the Journal of Prosthetic Dentistry:
AR. Mohammad, The Ohio State University, College of Dentistry Columbus, Ohio

A 30 patient trial in which DioxiDent liquid proved outstanding for the treatment of Candida albicans yeast infections of the mouth.

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Frontier Pharmaceutical, Inc.  10 Ponderosa Dr. Melville NY 11747
800-767-3486    631-367-3400    Fax: 631-692-7642
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